What is LUCENTIS & how can it help with treating macular edema (ME) following RVO?

LUCENTIS is a prescription medicine that is designed to block vascular endothelial (VASS‐cue‐ler end‐oh‐THEEL‐e‐ull) growth factor, or VEGF (vej‐EFF), from inside the eye. It was approved in 2010 to treat macular edema (ME) caused by RVO.

Click on the links below to learn more about VEGF & macular edema following retinal vein occlusion (RVO) and how LUCENTIS can help.

What is VEGF and what is VEGF's role in macular edema following RVO?

The eye contains a protein called vascular endothelial growth factor, or VEGF. The role of VEGF is to help grow new blood vessels.

  • Macular edema following retinal vein occlusion (RVO) is caused by an excess of VEGF in addition to vessel blockages. This leads to the abnormal blood vessel growth that can cause vision problems
  • The vision problems a retinal vein occlusion patient may experience will depend on which retinal vein blockage a patient is suffering from.

What is visual acuity?

Your doctor can detect changes or problems in your vision with a visual acuity test. Visual acuity tests find the smallest letters you can see on a standard eye chart.  
Visual acuity is the sharpness of your vision.

  • The farther down an eye chart you can see, the higher your visual acuity
  • Seeing more eye chart letters than before means that vision is getting better
  • Seeing fewer eye chart letters than before means that vision is getting worse

Visual acuity is expressed as a fraction such as 20/40 or a single number such as 1.5. 

  • The lower the bottom number in the fraction, the sharper your distance vision 

Following up with your doctor is necessary for tracking your vision over time and your progress with LUCENTIS.

How may LUCENTIS help people with macular edema following RVO?

Results from 2 studies showed:
LUCENTIS may help people with macular edema following RVO see more letters on an eye chart.

 

In a 6-month study of 263 people with macular edema following RVO:

 

 

In another 6-month study of 260 people with macular edema following RVO:

LUCENTIS may help improve* vision in people with macular edema following RVO

*Improvement means that they were able to see 15 or more letters on an eye chart.

 

In a 6-month study of 263 people with macular edema following RVO:

 

In another 6-month study of 260 people with macular edema following RVO:

How often are LUCENTIS treatments given to RVO patients?

Monthly treatments are recommended for patients with macular edema following RVO.

 

If you think you are experiencing problems with vision from RVO or sudden vision loss, make an appointment with a Retina Specialist right away.

If you do not have a Retina Specialist, ask your primary care physician or ophthalmologist about a referral.

Knowing what you may expect for your LUCENTIS treatment