Read about the safety information of LUCENTIS
LUCENTIS® (ranibizumab injection) is a prescription medicine for the treatment of patients with wet age-related macular degeneration (wAMD), macular edema following retinal vein occlusion (RVO), and diabetic macular edema (DME).
LUCENTIS is a prescription medication given by injection into the eye, and it has side effects. Some LUCENTIS patients have had detached retinas and serious infections inside the eye. You should not use LUCENTIS if you have an infection in or around the eye or are allergic to LUCENTIS or any of its ingredients.
Uncommonly, LUCENTIS patients have had serious, sometimes fatal, problems related to blood clots, such as heart attacks or strokes.
Some patients have had increased eye pressure before and within 1 hour of an injection.
Serious side effects include inflammation inside the eye and, rarely, problems related to the injection procedure, such as cataracts. These side effects can make your vision worse.
The most common eye-related side effects are increased redness in the white of the eye, eye pain, small specks in vision, and increased eye pressure. The most common non-eye-related side effects are nose and throat infections, headache, lung/airway infections, and nausea.
If your eye becomes red, sensitive to light, or painful, or if you have a change in vision, call or visit your eye doctor right away.
For additional safety information, please talk to your doctor and see the LUCENTIS full prescribing information.
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Wet age-related macular degeneration(wet AMD)
Macular edema following retinal vein occlusion(RVO)
LUCENTIS is supported by clinical research in RVO
LUCENTIS has been studied in patients with RVO since 2007 and was approved for its treatment by the FDA in 2010.
In 2 clinical trials, some patients given LUCENTIS could read additional letters as early as 7 days after their first treatment.
Not all patients on LUCENTIS experienced this result. Individual results may vary.
Possible serious side effects of LUCENTIS
Some patients continued improvements through month 6
In 2 clinical studies, patients receiving LUCENTIS monthly for 6 months gained more letters than those not receiving LUCENTIS.
BRVO, branch retinal vein occlusion; CRVO, central retinal vein occlusion.
What is visual acuity?
You've probably heard of 20/20 vision, which is considered normal vision. You can also see well with 20/40 vision. If you have 20/40 vision, you can typically sit near the back of a theater and see what's going on up front.
20/40 OR BETTER
Some patients maintained* or improved to 20/40 vision or better after 6 months.
In the BRVO study: up to 6 out of 10 patients† receiving LUCENTIS
In the CRVO study: up to 5 out of 10 patients‡ receiving LUCENTIS
Individual results may vary.
*Defined as losing fewer than 15 letters on an eye chart.
†Compared with 4 out of 10 patients not receiving LUCENTIS.
‡Compared with 2 out of 10 patients not receiving LUCENTIS.
LUCENTIS is a medicine that is injected by your doctor into the eye. Like all medicines, LUCENTIS has possible side effects. It is important for you to know what they are.
Talk with your eye doctor if you have:
Although it is uncommon, some people treated with LUCENTIS may have a life-threatening side effect.
Your doctor will stop treatment if any serious side effects occur. Be sure to contact your doctor if there are any signs of side effects.
Serious reactions have occurred related to the injection. They have happened in fewer than 0.1% (1 in 1,000) of people. These reactions can make your vision worse.
The retina is the light-sensitive layer of tissue that lines the inside of the eye. It sends visual messages through the optic nerve to the brain. When the retina detaches, it is lifted or pulled from its normal position.
A cataract is a clouding of the lens of the eye.
Some people have increased eye pressure before and within 1 hour after an injection. Your eye doctor should check your eyes and your eye pressure during the week after your injection.
A stroke happens when a blood vessel that carries oxygen to the brain is either blocked by a clot or bursts. This means that part of the brain cannot get the oxygen it needs. As a result, the brain gets damaged.
A heart attack happens when a blood vessel that carries oxygen to the heart is either blocked by a clot or bursts. This means that part of the heart cannot get the oxygen it needs. As a result, the heart gets damaged.
Call or visit your eye doctor right away if:
Here are the most common eye-related side effects in clinical studies of LUCENTIS:
Here are the most common non-eye-related side effects in clinical studies of LUCENTIS:
LUCENTIS is for prescription use only.