Retinal Vein Occlusion Glossary – LUCENTIS® (ranibizumab injection)

	Branch retinal vein occlusion (o-kloo-zhun) (or branch RVO, or BRVO)

A type of retinal vein occlusion in which the vein blockage occurs in the inner portion of the eye, where the retinal veins “branch out” into smaller veins.
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	Central retinal vein occlusion (o-kloo-zhun) (or central RVO, or CRVO)

A type of retinal vein occlusion in which the vein blockage occurs in the central or main retinal vein at the back of the eye.
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	ETDRS eye chart

A type of eye chart used in clinical trials to test and measure patients' vision. ETDRS stands for Early Treatment of Diabetic Retinopathy Study.
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	FDA (US Food and Drug Administration)

The agency of the US Department of Health and Human Services that regulates food and drug products to help determine their safety and proper usage. Back to top

	Fluorescein angiogram (floor-re-seen an-jee-o-gram)

A test that examines the blood circulation of the retina. It is used by your Retina Specialist to evaluate your condition and help determine the course of your treatment. Back to top

	Glaucoma (glow-coma)

A disease in which the optic nerve is damaged, leading to progressive, irreversible loss of vision. Glaucoma is often associated with abnormally high pressure in the eye. Back to top

	Macula (mak-yoo-luh)

The part of your eye responsible for central vision. Back to top

	Macular edema (mak-yoo-lar eh-dee-muh)

The buildup of fluid in the macula that can lead to swelling of the macula. Back to top

	OCT scans

Pictures taken using optical coherence tomography that help your Retina Specialist detect and monitor the buildup of fluid in the macula (macular edema). Back to top

	Ophthalmoscope (op-thal-muh-scope)

An instrument your Retina Specialist may use to look into the back of your eye to help evaluate the severity of RVO. Back to top

	Optical coherence tomography (to-mog-ruh-fee) (or OCT)

A system used to obtain detailed pictures from within your retina. Back to top

	Retina

The layered nerve tissue that lines the back of the eye, senses light, and creates impulses that travel through the optic nerve to the brain. Back to top

	Retina Specialist

A surgeon who specializes in treating a range of diseases of the back of the eye (or retina). He or she is an ophthalmologist who has completed an additional 1 to 2 years of specialty training. Back to top

	Retinal vein occlusion (o-kloo-zhun) (or RVO)

The blockage of a vein in your eye that can lead to vision loss in the affected eye. Back to top

	US Food and Drug Administration (FDA)

The agency of the US Department of Health and Human Services that regulates food and drug products to help determine their safety and proper usage. Back to top

	VEGF (or vascular endothelial growth factor)

A protein in your body that helps the growth of new blood vessels. While normally beneficial to your body, VEGF can lead to complications with your vision when you have RVO. Back to top

	Visual acuity

The ability to see fine detail clearly. Your Retina Specialist will test your visual acuity regularly with eye charts to monitor your condition. Your visual acuity is rated using numbers that describe how well you can see. For instance, 20/20 is considered perfect vision, while 20/200 or worse (with corrective lenses) is considered legal blindness. Back to top

Who is LUCENTIS for?

LUCENTIS^® (ranibizumab injection) is a prescription medicine for the treatment of patients with macular edema following retinal vein occlusion (RVO).

What important safety information should I know about LUCENTIS?

LUCENTIS is a prescription medication given by injection into the eye, and it has side effects. Some LUCENTIS patients have had detached retinas and serious infections inside the eye. You should not use LUCENTIS if you have an infection in or around the eye or are allergic to LUCENTIS or any of its ingredients.

Uncommonly, LUCENTIS patients have had serious, sometimes fatal, problems related to blood clots, such as heart attacks or strokes.

Some patients have had increased eye pressure within 1 hour of an injection.

Serious side effects include inflammation inside the eye and, rarely, problems related to the injection procedure, such as cataracts. These side effects can make your vision worse.

The most common eye-related side effects are increased redness in the white of the eye, eye pain, small specks in vision, and the feeling that something is in the eye. The most common non–eye-related side effects are nose and throat infections, headache, and lung/airway infections.

If your eye becomes red, sensitive to light, or painful, or if you have a change in vision, call or visit your eye doctor right away.

For additional safety information, please talk to your doctor and see the LUCENTIS full prescribing information.

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