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LUCENTIS and retinal vein occlusion

LUCENTIS® (ranibizumab injection) is what's known as an anti-VEGF medication. Anti-VEGF agents can be used to treat macular edema following retinal vein occlusion. These medications are given as an injection in the eye.

The history of LUCENTIS

Retina Specialists have been using LUCENTIS for several years to help patients with another eye condition known as wet age-related macular degeneration (AMD).
 
2010
Following a review of the results from the 2007 clinical trials, the FDA approved LUCENTIS for the treatment of patients with macular edema following retinal vein occlusion. See the results
 
2007
In 2007, clinical trials began to study the safety and effectiveness of LUCENTIS in treating patients with macular edema following retinal vein occlusion.
 
2006
In June 2006, LUCENTIS was approved by the FDA for wet AMD.

Important Safety Information

Like other injections given into the eye, serious eye infection (endophthalmitis) and detached retina have occurred with LUCENTIS. Increases in eye pressure have been seen within 1 hour of an injection.


Who is LUCENTIS for?

LUCENTIS® (ranibizumab injection) is a prescription medicine for the treatment of patients with Macular Edema following Retinal Vein Occlusion (RVO).

What important safety information should I know about LUCENTIS?

LUCENTIS is a prescription medication given by injection into the eye, and it has side effects. LUCENTIS is not for everyone. You should not use LUCENTIS if you have an infection in or around the eye or are allergic to LUCENTIS or any of its ingredients.

Some LUCENTIS patients have serious side effects related to the injection. These include serious infections inside the eye, detached retinas, and cataracts. Other uncommon serious side effects include inflammation inside the eye and increased eye pressure. These can make your vision worse. Some patients have increases in eye pressure within 1 hour of an injection. Your eye doctor should check your eye pressure and eye health during the week after your LUCENTIS injection.

Although not common, LUCENTIS patients have had eye- and non–eye-related blood clots (heart attacks, strokes, and death).

If your eye becomes red, sensitive to light, painful, or has a change in vision, you should call or visit your eye doctor right away.

The most common side effects to your eye are increased redness in the whites of your eye, eye pain, small specks in vision, and the feeling that something is in your eye. The most common non–eye-related side effects are nose and throat infections, headache, and respiratory (lung) infections.

LUCENTIS is for prescription use only.

For additional safety information, please talk to your doctor and see the LUCENTIS full prescribing information