That's My
That's My


LUCENTIS is supported by 3 years of clinical research in DME

LUCENTIS was studied in approximately 500 patients, in 2 clinical trials lasting 3 years each. In 2012, LUCENTIS was FDA-approved to treat DME.

DME patients had improvements in vision in 2 clinical trials
  • Patients gained an average of 11.7 letters at 2 years
  • Some patients could read additional letters as early as day 7

Not all patients on LUCENTIS experienced this result. Individual results may vary.

Possible serious side effects of LUCENTIS

Serious side effects include inflammation inside the eye and, rarely, problems related to the injection procedure, such as cataracts. These side effects can make your vision worse.

Some patients gained 15 letters or more

In 2 clinical studies lasting 3 years, up to 4 out of 10 patients receiving LUCENTIS each month gained 15 letters or more on an eye chart, compared with 2 out of 10 patients not receiving LUCENTIS, when measured at 2 years.

A person with DME may be able to read only a few letters on the eye chart.

Someone receiving LUCENTIS may be able to see an additional 15 letters.*

* Individual results may vary.

In these studies, patients continued to receive LUCENTIS treatment over a 3-year period. Some of these patients saw significant improvement throughout their first year and some patients lost letters. Of patients who gained letters, some kept those gains throughout the second and third year.

What does it mean to see 15 more letters?

Your Retina Specialist uses an eye chart to measure your vision. The farther down the chart you can see— as the letters get smaller—the better your vision.

What is visual acuity?

You've probably heard of 20/20 vision. That's a measure of visual acuity, and 20/20 is normal vision. A person with 20/20 vision can stand 20 feet from something and see it clearly.

20/40 is also a good score. People with 20/40 vision usually do not have trouble with reading, seeing small letters, or watching sporting events.

With LUCENTIS, you could improve your visual acuity.

Partner with your Retina Specialist and get LUCENTIS treatments as recommended.

Important safety information

What are the side effects with LUCENTIS?

Possible serious side effects

LUCENTIS is a medicine that is injected by your doctor into the eye. Like all medicines, LUCENTIS has possible side effects. It is important for you to know what they are.

LUCENTIS is not for everyone

Talk with your eye doctor if you have:

  • Infections in or around the eye
  • An allergy to LUCENTIS or any of its ingredients

Although it is uncommon, some people treated with LUCENTIS may have a life-threatening side effect.

Your doctor will stop treatment if any serious side effects occur. Be sure to contact your doctor if there are any signs of side effects.

  • Serious infections inside the eye
  • Detached retinas

    The retina is the light-sensitive layer of tissue that lines the inside of the eye. It sends visual messages through the optic nerve to the brain. When the retina detaches, it is lifted or pulled from its normal position.

  • Cataracts

    A cataract is a clouding of the lens of the eye.

Other side effects that are serious but not common include:

  • Inflammation (swelling) inside the eye
  • Increased eye pressure

    Some people have increased eye pressure before and within 1 hour after an injection. Your eye doctor should check your eyes and your eye pressure during the week after your injection.

Serious side effects (uncommon, but sometimes fatal)

  • Strokes

    A stroke happens when a blood vessel that carries oxygen to the brain is either blocked by a clot or bursts. This means that part of the brain cannot get the oxygen it needs. As a result, the brain gets damaged.

  • Heart attacks

    A heart attack happens when a blood vessel that carries oxygen to the heart is either blocked by a clot or bursts. This means that part of the heart cannot get the oxygen it needs. As a result, the heart gets damaged.

  • Other problems related to blood clots

When to call your doctor

Call or visit your eye doctor right away if:

Your eye becomes red, painful, or sensitive to light
You have a change in your vision

Most common eye-related side effects

Here are the most common eye-related side effects in clinical studies of LUCENTIS:

  • Increased redness in the white part of the eye
  • Cataract
  • Increased eye pressure

Most common non-eye-related side effects

Here are the most common non-eye-related side effects in clinical studies of LUCENTIS:

  • Nose and throat infections
  • Decrease in the number of red blood cells
  • Nausea

LUCENTIS is for prescription use only.

You may report side effects to the FDA at (800) FDA-1088 or You may also report side effects to Genentech at (888) 835-2555.

For additional safety information, please talk to your doctor and see the LUCENTIS full prescribing information.

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