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What is LUCENTIS?

LUCENTIS® (ranibizumab injection) is a prescription medicine that you may receive from your Retina Specialist. It was approved by the FDA in 2006.

How LUCENTIS may work

The eye

The retina is a thin film at the back of your eye. It's the part of the eye that captures what you see. The macula looks like an indent in the retina.

It helps you see details.

Vision loss

If your doctor prescribed you LUCENTIS, that means your eye contains extra amounts of a protein called VEGF. It is one of the causes of leaky, abnormal blood vessels. The excess fluid that comes from these blood vessels can accumulate and lead to changes in your vision.

How LUCENTIS can help

LUCENTIS is designed to block VEGF. That's why it's called an anti-VEGF. By blocking VEGF, LUCENTIS may prevent damaged blood vessels from leaking fluid into the macula. This can reduce swelling.

LUCENTIS was designed specifically for use in the eye. It was also designed so the body can remove it quickly when it leaves the eye.

Who LUCENTIS is for

LUCENTIS is used for the treatment of patients with wet age-related macular degeneration (wet AMD), diabetic macular edema (DME), and the 2 forms of macular edema following retinal vein occlusion (RVO): branch RVO (BRVO) and central RVO (CRVO).

Frequently asked questions (Click the arrow boxes to get answers)

  • What is LUCENTIS?
    LUCENTIS is the first FDA-approved medicine to treat wet age-related macular degeneration (wet AMD), diabetic macular edema (DME), and the 2 forms of macular edema following retinal vein occlusion (RVO): branch RVO (BRVO) and central RVO (CRVO).
  • How long has LUCENTIS been used to treat patients?
    LUCENTIS was approved by the FDA in 2006. It was the first anti-VEGF to be approved to treat wet AMD, DME, and the 2 forms of macular edema following retinal vein occlusion (RVO): branch RVO (BRVO) and central RVO (CRVO).
  • What are the side effects of LUCENTIS?
    Serious side effects include inflammation inside the eye and, rarely, problems related to the injection procedure, such as cataracts. These side effects can make your vision worse.

    The most common eye-related side effects are increased redness in the white of the eye, eye pain, small specks in vision, and increased eye pressure. The most common non–eye-related side effects are nose and throat infections, headache, lung/airway infections, and nausea.

    For additional safety information, please talk to your doctor and see the LUCENTIS full prescribing information.

  • How is LUCENTIS given?
    LUCENTIS is given by an injection into your eye. Your Retina Specialist will first clean and then numb your eye to limit discomfort before giving you the injection.
  • How often will I receive LUCENTIS?
    The number of treatments you receive will depend on your condition and on what your Retina Specialist thinks is best for you. For wet AMD, LUCENTIS may be given monthly or less frequently. For DME and RVO, LUCENTIS is given monthly.
  • What if I miss a dose of LUCENTIS?
    Speak to your Retina Specialist about the recommended dosing schedule for your treatment. If you have missed an appointment for a LUCENTIS treatment, call your Retina Specialist to find out when you should schedule an appointment for your next treatment.
  • Who should not use LUCENTIS?
    LUCENTIS should not be used in patients who have an infection in or around the eye or are allergic to LUCENTIS or any of its ingredients.
  • What should I expect following a LUCENTIS treatment?
    • You may have some redness on the white part of your eye at the injection site
    • You may see a few specks in your vision
    • Your Retina Specialist may give you antibiotic eyedrops to use for a few days after the treatment to help prevent infection
    • Ask your Retina Specialist if you should avoid any activities
    • If your eye becomes red, sensitive to light, painful, or has a change in vision, you should seek immediate care from your Retina Specialist
    • Some people experience an improvement in their vision as early as day 7, but not all patients on LUCENTIS gained or maintained vision. Individual results may vary
    There are other side effects you may experience.

    For additional safety information, please talk to your doctor and see the LUCENTIS full prescribing information.

  • How soon can I expect results with LUCENTIS?
    Individual results may vary. In clinical trials, some people experienced improvement in their vision as early as day 7. For other people, it took longer for their vision to improve, and some people did not experience any improvement. Talk to your doctor about your treatment and what to expect.
  • What is the LUCENTIS Patient Support Program?
    The LUCENTIS Patient Support Program is a free program that offers you information on your LUCENTIS treatment, managing your vision loss, and lifestyle tips. You can receive the information through the mail and e-mail.

    Learn more about the LUCENTIS Patient Support Program.

  • Are there any services to help me pay for LUCENTIS?
    At Genentech, we believe all medicines should be accessible to the patients who need them, so we've created 2 different types of support programs.

    LUCENTIS Access Solutions is for people who have questions about their insurance, are on Medicare, or have no insurance.

    The LUCENTIS Co-Pay Card Program is only for patients with “commercial” or “private” insurance. This means that if you have government-funded insurance, such as Medicare or Medicaid, you are not currently eligible for the card. This program can help reduce out-of-pocket costs for eligible LUCENTIS patients, regardless of income.

    If you are eligible, the card acts just like extra insurance and can cover up to 80% of the cost of LUCENTIS not covered by your regular insurance.

    Learn more about insurance coverage and payment options.

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Who is LUCENTIS for?

LUCENTIS® (ranibizumab injection) is a prescription medicine for the treatment of patients with wet age-related macular degeneration (wAMD), macular edema following retinal vein occlusion (RVO), and diabetic macular edema (DME).

What important safety information should I know about LUCENTIS?

LUCENTIS is a prescription medication given by injection into the eye, and it has side effects. Some LUCENTIS patients have had detached retinas and serious infections inside the eye. You should not use LUCENTIS if you have an infection in or around the eye or are allergic to LUCENTIS or any of its ingredients.

Uncommonly, LUCENTIS patients have had serious, sometimes fatal, problems related to blood clots, such as heart attacks or strokes.

Some patients have had increased eye pressure before and within 1 hour of an injection.

Serious side effects include inflammation inside the eye and, rarely, problems related to the injection procedure, such as cataracts. These side effects can make your vision worse.

The most common eye-related side effects are increased redness in the white of the eye, eye pain, small specks in vision, and increased eye pressure. The most common non-eye-related side effects are nose and throat infections, headache, lung/airway infections, and nausea.

If your eye becomes red, sensitive to light, or painful, or if you have a change in vision, call or visit your eye doctor right away.

For additional safety information, please talk to your doctor and see the LUCENTIS full prescribing information.