That's My
That's My

About DME

Understanding how diabetes can affect your vision and cause DME is a great first step toward understanding how to manage it.

DME occurs in people who have leaky blood vessels in the retina. This is known as diabetic retinopathy. When DME happens, damaged blood vessels leak fluid into the macula. This causes the macula to swell. DME can cause blurry, washed-out vision.

DME and the eye

The retina is a thin film at the back of your eye. It’s the part of the eye that captures what you see. Near the center of the retina is the macula, which is responsible for sharp, detailed vision.

Healthy retina

In a healthy retina, the fovea (the centermost part of the macula) will appear indented.

Retina with DME

In an eye with DME, blood vessels leak. Fluid collects in the retina and macula. This causes the macula to swell and bulge. With a swollen macula, it can be hard to see fine detail.

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What important safety information should I know about LUCENTIS?

You should not use LUCENTIS if you have an infection in or around the eye or are allergic to LUCENTIS or any of its ingredients. LUCENTIS is a prescription medication given by injection into the eye, and it has side effects. LUCENTIS is not for everyone. Some LUCENTIS patients have serious side effects related to the injection. These include serious infections of the eye, detached retinas, and cataracts. Other uncommon serious side effects include inflammation inside the eye and increased eye pressure. These side effects can make your vision worse. Some patients have had increased eye pressure before and within 1 hour of an injection. Your eye doctor should check your eye pressure and eye health after your LUCENTIS injection.

Uncommonly, LUCENTIS patients have had serious, sometimes fatal, problems related to blood clots, such as heart attacks or strokes.

Some patients have had increased eye pressure before and within 1 hour of an injection.

Serious side effects include inflammation inside the eye and, rarely, problems related to the injection procedure, such as cataracts. These side effects can make your vision worse.

The most common eye-related side effects are increased redness in the white of the eye, cataract, and increased eye pressure. The most common non–eye-related side effects are nose and throat infections, anemia, and nausea.

If your eye becomes red, sensitive to light, or painful, or if you have a change in vision, call or visit your eye doctor right away.

You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555.

For additional safety information, please talk to your doctor and see the LUCENTIS full prescribing information.

Who is LUCENTIS for?

LUCENTIS® (ranibizumab injection) is a prescription medicine for the treatment of patients with diabetic macular edema (DME).

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